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UPenn Fights Influenza:
Baby, Be Wise -- Immunize!

Using song and lyrics to raise awareness of the importance of influenza vaccination for HCWs, the Hospital of the University of Pennsylvania created this 5-minute video featuring scores of employees lip-synching to a doo-wop beat.
Information for Healthcare Professionals
Influenza - prevent a bad disease with a good vaccine!
Vaccine Production, Ordering, and Distribution
Seasonal Influenza Vaccines for 2009-2010
Manufacturer Trade Name Presentation Mercury
Content
(mcg
Hg/0.5
mL dose)
Age Indication
CSL Biotherapies Afluria 0.5 mL (single-dose syringe) 0 36 months & older
24.5 6 months & older
5.0 mL (mullti-dose vial)
GlaxoSmithKline (GSK) Fluarix 0.5 mL (single-dose syringe) 0 3 years & older
ID Biomedical Corporation of Quebec
(Distributed by GlaxoSmithKline)
FluLaval 5.0 mL (10-dose vial) 25 18 years & older
MedImmune FluMist 0.2 mL (single-use sprayer) 0 2 through 49 years
Novartis Vaccines Fluvirin 0.5 mL (single-dose syringe) <1 4 years and older
5.0 mL (10-dose vial) 25
Agiflu 0.5 mL (single-dose syringe) 0

18 years & older

sanofi pasteur FluZone 0.25 mL (single-dose syringe) 0 6 through 35 months
0.5 mL (single-dose syringe) 0 36 months & older
0.5 mL (single-dose vial) 0 36 months & older
5.0 mL (multi-dose vial) 25 6 months & older
Influenza A (H1N1) 2009 Monovalent Vaccines
Manufacturer Presentation Mercury Content
(mcg Hg/0.5 mL dose)
Age Indication
CSL Biotherapies

0.5 mL (single-dose syringe)

0 36 months & older
24.5 6 months & older
5.0 mL (multi-dose vial)
ID Biomedical Corporation of Quebec
(Distributed by GlaxoSmithKline)
5.0 mL (10-dose vial) 25 18 years & older
MedImmune

0.2 mL (single-use sprayer)

0 2 through 49 years
Novartis Vaccines 0.5 mL (single-dose syringe) <1 4 years and older
5.0 mL (10-dose vial) 25
sanofi pasteur 0.25 mL (single-dose syringe) 0 6 through 35 months
0.5 mL (single-dose syringe) 0 36 months & older
0.5 mL (single-dose vial) 0 36 months & older
5.0 mL (multi-dose vial) 25 6 months & older

Seasonal Influenza Vaccine Ordering
Most providers order influenza vaccine for the coming vaccination season in the winter and spring of the preceding year. Depending on many factors, orders can be placed direct with the manufacturer, with a distributor, the state's VFC program, or a group purchasing arrangement.

Once the vaccination season is under way, the Influenza Vaccine Availability Tracking System (IVATS) also becomes operational. IVATS enables healthcare providers to view at a glance which distributors have vaccine available to sell.

Order from a manufacturer: To order either Fluarix (GSK) or FluZone (sanofi pasteur), contact the manufacturer.

Order from a distributor: To order FluLaval (GSK), FluMist (MedImmune), or FluVirin (Novartis), contact one of the many distributors that you will find here.

View vaccine currently for sale on the Influenza Vaccine Availability Tracking System (IVATS), a product of the National Influenza Vaccine Summit.

H1N1 Influenza Vaccine Ordering and Distribution
View a flow chart of the ordering process and distribution chain for both seasonal and H1N1 influenza vaccines.

Read a report about how the distribution process for H1N1 and seasonal influenza vaccine differs and how medical products, including vaccine, are allocated in times of high demand or scarcity. Also included in the report are links to each state health department's website that explain how healthcare providers should register to be a provider of H1N1 vaccine, and more.

Interested in Learning More About Influenza Vaccine Production?
Read a report from the Health Industry Distributors Association, a non-profit trade association of medical products distributors who service healthcare providers, that explains the process that determines when and how vaccine reaches doctors, hospitals, nursing homes, and others.

Understanding the Dynamics of Influenza Vaccine Supply and Demand -- Five Issue Briefs. This series of briefs were prepared for the Assistant Secretary for Planning and Evaluation of the Department of Health and Human Services in October 2005.

Overview -- Summary and Assessment: roles and responsibilities of the influenza vaccine stakeholders.
 
Vaccine Economics: characteristics of the influenza vaccine market, industry regulatory requirements for vaccine productions, and factors affecting the profitability of vaccine production.


Who Buys It and Who Sells It: the vaccine supply chain and potential means for facilitating vaccine purchase and distribution.


Vaccine Manufacturing: the unique characteristics of the influenza vaccine, the structure of the industry, decisions about the amount of vaccine produced each year, investments in new technologies, and other factors.

The Chicken and the Egg: factors that impact the demand for vaccine and how they can affect supply.

American Medical Association: Science, Research, and Technology
Litjen (L.J.) Tan, PhD litjen.tan@ama-assn.org

515 N. State St.  •  Chicago, IL 60610

This website managed by the Immunization Action Coalition
Diane Peterson, editor  •  Mitch Rothholz, RPh, MBA, contributing editor